New air-stable catalysts for general and efficient suzuki-miyaura cross-coupling reactions of heteroaryl chlorides.

نویسندگان

  • Anil S Guram
  • Anthony O King
  • John G Allen
  • Xianghong Wang
  • Laurie B Schenkel
  • Johann Chan
  • Emilio E Bunel
  • Margaret M Faul
  • Robert D Larsen
  • Michael J Martinelli
  • Paul J Reider
چکیده

[reaction: see text] New air-stable PdCl(2){P(t)Bu(2)(p-R-Ph)}(2) (R = H, NMe(2), CF(3),) complexes represent simple, general, and efficient catalysts for the Suzuki-Miyaura cross-coupling reactions of aryl halides including five-membered heteroaryl halides and heteroatom-substituted six-membered heteroaryl chlorides with a diverse range of arylboronic acids. High product yields (89-99% isolated yields) and turn-over-numbers (10,000 TON) are observed.

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عنوان ژورنال:
  • Organic letters

دوره 8 9  شماره 

صفحات  -

تاریخ انتشار 2006